Chit-Chatting: Was biblical Cain the first Vampire?

*Stands in the road looking at the passersby wondering the best way to approach. The proverbial light bulb goes on and she says...*

Hello my amazing followers, I have a questions that I will love to ask you. I'm hoping that I can engage you in conversation; get to know your opinions a bit better. So...

What's your take on the whole "Cain as the original Vampire" trend that's going around?

Background:
I just began a vampire book called Grace Through Blood, and the very first thing that can be read is a Bible quote (the book only uses verses 10, 12 and 15):

¹⁰And he said, What hast thou done? the voice of thy brother's blood crieth unto me from the ground. ¹¹And now art thou cursed from the earth, which hath opened her mouth to receive thy brother's blood from thy hand; ¹²When thou tillest the ground, it shall not henceforth yield unto thee her strength; a fugitive and a vagabond shalt thou be in the earth. ¹³And Cain said unto the Lord, My punishment is greater than I can bear. ¹⁴Behold, thou hast driven me out this day from the face of the earth; and from thy face shall I be hid; and I shall be a fugitive and a vagabond in the earth; and it shall come to pass, that every one that findeth me shall slay me. ¹⁵And the Lord said unto him, Therefore whosoever slayeth Cain, vengeance shall be taken on him sevenfold. And the Lord set a mark upon Cain, lest any finding him should kill him. 

 —Genesis 4:10-15. King James Version (KJV)

This isn't the first time I come across this concept. Author Jeaniene Frost uses it in her Night Huntress series when she explains the origins of vampires saying that Cain is the father of all Vampires (and Ghouls). Author Cassandra Clare dabbles a little in the subject when Clary Fray (from The Mortal Instruments) SPOILER ALERT: uses Cain’s Mark to single out and protect her best friend Simon (a vampire). END OF SPOILER A quick Google search shows that a video game from 1991, "Vampire: The Masquerade," also plays with this concept. There are many other references that can be found but the gist of the matter is that Cain was turned into the first vampire by God as punishment for committing the first murder.

Now, the Questions:

I want to know, what are your thoughts on the whole concept? From a fiction stand point, do you think the concept is believable? Or do you prefer the alter storylines: vampires as either demons or genetic mutations, biological evolution? Which is your favorite vampire explanation?

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